GB7300.503-2023

Feed additives —Part 5：Live microorganisms — Enterococcus faecium

饲料添加剂第5部分：微生物屎肠球菌

GB 7300.503-2023 ist eine gültige verbindliche chinesische Nationalnorm: Feed additives —Part 5：Live microorganisms — Enterococcus faecium. Branchencluster: Lebensmittel. Schwerpunkt: Produktsicherheit. Inkrafttreten: 1. Juni 2024.

Die Anwendbarkeit hängt vom Produktumfang, dem Zertifizierungsweg, Bekanntmachungen der Behörden und Übergangsregeln ab. Fordern Sie eine Übersetzung an oder prüfen Sie die Quelle, bevor Sie diesen Eintrag für Compliance-Entscheidungen nutzen.

Compliance-Überblick

Dieser Überblick ist derzeit nur auf Englisch verfügbar.

Geltungsbereich und Anwendbarkeit

This standard applies to feed additive products containing Enterococcus faecium, which are produced through liquid or solid-state fermentation and subsequent drying processes. It is mandatory for manufacturers producing microbial feed additives intended for the Chinese animal nutrition market. It does not apply to other live microorganisms or non-microbial feed additive categories.

Technische Anforderungen

The standard outlines the physical, chemical, and biological parameters for Enterococcus faecium. It specifies that raw materials such as carriers and diluents must comply with the national feed hygiene standard GB 13078. The product must present as a uniform powder or granule without foreign matter or off-odors. For the microbial strain itself, it must meet specific morphological, physiological, biochemical, and molecular biology characteristics. The standard strictly regulates the viable bacteria count and moisture content to ensure product stability and efficacy. Furthermore, the standard sets strict hygiene limits for heavy metals (such as lead, arsenic, mercury, and cadmium) and mycotoxins (including aflatoxin B1 and zearalenone). Pathogenic microorganisms like Salmonella must not be detected. A critical safety requirement is the ampicillin sensitivity parameter. The strain must demonstrate susceptibility to ampicillin, ensuring it does not carry transferable antibiotic resistance genes.

Prüfverfahren

The standard mandates specific testing protocols to verify compliance. Strain identification involves morphological observation on selective media, physiological and biochemical tests, and 16S rRNA gene sequence analysis. Viable bacteria counting is conducted using specialized MRS media. Physicochemical and hygiene parameters are tested using referenced national standards, such as GB/T 6435 for moisture and GB/T 13080 for lead. Microbial contamination levels for Salmonella and coliforms are evaluated using corresponding GB/T methods. Additionally, the ampicillin Minimum Inhibitory Concentration (MIC) is determined following ISO 20776-1:2006.

Häufige Fragen

What products are regulated under GB 7300.503-2023?

This standard applies specifically to feed additive products containing Enterococcus faecium, which are produced through liquid or solid-state fermentation and subsequent drying processes. It is mandatory for all manufacturers producing and selling this specific microbial feed additive in China.

Are there any specific safety or antibiotic resistance requirements in GB 7300.503-2023?

The standard introduces updated and highly specific requirements for strain identification, including 16S rRNA molecular biology sequencing, and sets a strict limit for ampicillin sensitivity (MIC ≤ 2mg/L) to ensure the safety and efficacy of the Enterococcus faecium strain.

How does GB 7300.503-2023 differ from ISO standards?

The standard references several national methodologies for testing hygiene and physicochemical parameters. Notably, for evaluating the ampicillin MIC value, it directly references ISO 20776-1:2006 for the testing procedure.

The summary above provides a high-level overview of GB 7300.503-2023. To ensure complete compliance for your feed additive products entering the Chinese market, a precise and professional translation of the full technical specifications is essential. Purchase our high-quality English translation of GB 7300.503-2023 today to access all detailed parameters, tables, and testing procedures.

Hinweise zur Anwendbarkeit

Normtyp: Produkt
CCS: B46
ICS: 65.120
Zuständige Behörde: Ministry of Agriculture and Rural Affairs
Technisches Komitee: Ministry of Agriculture and Rural Affairs